H-bonding mediates polarization of peptide groups in folded proteins
نویسندگان
چکیده
منابع مشابه
Category of $H$-groups
This paper develops a basic theory of $H$-groups. We introduce a special quotient of $H$-groups and extend some algebraic constructions of topological groups to the category of H-groups and H-maps and then present a functor from this category to the category of quasitopological groups.
متن کاملGaussian Dynamics of Folded Proteins
Vibrational dynamics of folded proteins is studied using a Gaussian model in which the protein is viewed as a network, residues representing the junctions, and the connectivity being established by a single parameter harmonic potential. Application to seven proteins showed that the local packing density plays a major role in determining the vibrational spectrum at time scales of picoseconds. At...
متن کاملTopological solitons and folded proteins.
We argue that protein loops can be described by topological domain-wall solitons that interpolate between ground states which are the α helices and β strands. We present an energy function that realizes loops as soliton solutions to its equation of motion, and apply these solitons to model a number of biologically active proteins including 1VII, 2RB8, and 3EBX (Protein Data Bank codes). In all ...
متن کاملContribution of charged groups to the enthalpic stabilization of the folded states of globular proteins.
In this paper we use the results from all-atom molecular dynamics (MD) simulations of proteins and peptides to assess the individual contribution of charged atomic groups to the enthalpic stability of the native state of globular proteins and investigate how the distribution of charged atomic groups in terms of solvent accessibility relates to protein enthalpic stability. The contributions of c...
متن کاملTwin-arginine-dependent translocation of folded proteins.
Twin-arginine translocation (Tat) denotes a protein transport pathway in bacteria, archaea and plant chloroplasts, which is specific for precursor proteins harbouring a characteristic twin-arginine pair in their signal sequences. Many Tat substrates receive cofactors and fold prior to translocation. For a subset of them, proofreading chaperones coordinate maturation and membrane-targeting. Tat ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Protein Science
سال: 2009
ISSN: 0961-8368
DOI: 10.1110/ps.03127103